Carbonic anhydrase modulation of emotional memory. Implications for the treatment of cognitive disorders
Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes which use CO2 as substrate, catalysing its interconversion to bicarbonate and a proton.In humans 15 CAs are expressed, 12 of which are catalytically active: the cytosolic CA I-III, VII, XIII, the sophie allport bee curtains membrane-bound CA IV, the mitochondrial CA VA and VB, the secreted CA